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CD73-A2a adenosine receptor axis promotes innate B cell antibody responses to pneumococcal polysaccharide vaccination

Many individuals at risk of streptococcal infection respond poorly to the pneumococcal polysaccharide vaccine Pneumovax 23. Identification of actionable pathways able to enhance Pneumovax responsiveness is highly relevant. We investigated the contribution of the extracellular adenosine pathway regul...

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Detalles Bibliográficos
Autores principales: Allard, David, Charlebois, Roxanne, Gilbert, Loise, Stagg, John, Chrobak, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788373/
https://www.ncbi.nlm.nih.gov/pubmed/29377929
http://dx.doi.org/10.1371/journal.pone.0191973