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Destructive cellular paths underlying familial and sporadic Parkinson disease converge on mitophagy

The knowledge gap separating the molecular and cellular underpinnings of Parkinson disease (PD) and its pathology hinders treatment innovation. Adding to this difficulty is the lack of a reliable biomarker for PD. Our previous studies identify a link of 2 PD proteins, PINK1/PRKN Parkin to a mitochon...

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Detalles Bibliográficos
Autor principal: Wang, Xinnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788483/
https://www.ncbi.nlm.nih.gov/pubmed/28598236
http://dx.doi.org/10.1080/15548627.2017.1327511