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Legionella blocks autophagy by cleaving STX17 (syntaxin 17)

Pathogens subvert host defense systems including autophagy and apoptosis for their survival and proliferation. Legionella pneumophila is a Gram-negative bacterium that grows in alveolar macrophages and causes severe pneumonia. Early during infection Legionella secretes effector proteins that convert...

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Detalles Bibliográficos
Autores principales: Arasaki, Kohei, Tagaya, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788486/
https://www.ncbi.nlm.nih.gov/pubmed/28933649
http://dx.doi.org/10.1080/15548627.2017.1371395