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Structure-based membrane dome mechanism for Piezo mechanosensitivity

Mechanosensitive ion channels convert external mechanical stimuli into electrochemical signals for critical processes including touch sensation, balance, and cardiovascular regulation. The best understood mechanosensitive channel, MscL, opens a wide pore, which accounts for mechanosensitive gating d...

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Detalles Bibliográficos
Autores principales: Guo, Yusong R, MacKinnon, Roderick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788504/
https://www.ncbi.nlm.nih.gov/pubmed/29231809
http://dx.doi.org/10.7554/eLife.33660