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Structure-based membrane dome mechanism for Piezo mechanosensitivity
Mechanosensitive ion channels convert external mechanical stimuli into electrochemical signals for critical processes including touch sensation, balance, and cardiovascular regulation. The best understood mechanosensitive channel, MscL, opens a wide pore, which accounts for mechanosensitive gating d...
Autores principales: | Guo, Yusong R, MacKinnon, Roderick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788504/ https://www.ncbi.nlm.nih.gov/pubmed/29231809 http://dx.doi.org/10.7554/eLife.33660 |
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