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Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets

Ewing sarcoma is an undifferentiated small-round-cell sarcoma. Although molecular detection of pathognomonic EWSR1-ETS fusions such as EWSR1-FLI1 enables definitive diagnosis, substantial confusion can arise if molecular diagnostics are unavailable. Diagnosis based on the conventional immunohistoche...

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Detalles Bibliográficos
Autores principales: Baldauf, Michaela C., Orth, Martin F., Dallmayer, Marlene, Marchetto, Aruna, Gerke, Julia S., Rubio, Rebeca Alba, Kiran, Merve M., Musa, Julian, Knott, Maximilian M. L., Ohmura, Shunya, Li, Jing, Akpolat, Nusret, Akatli, Ayse N., Özen, Özlem, Dirksen, Uta, Hartmann, Wolfgang, de Alava, Enrique, Baumhoer, Daniel, Sannino, Giuseppina, Kirchner, Thomas, Grünewald, Thomas G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788584/
https://www.ncbi.nlm.nih.gov/pubmed/29416716
http://dx.doi.org/10.18632/oncotarget.20098