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Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets
Ewing sarcoma is an undifferentiated small-round-cell sarcoma. Although molecular detection of pathognomonic EWSR1-ETS fusions such as EWSR1-FLI1 enables definitive diagnosis, substantial confusion can arise if molecular diagnostics are unavailable. Diagnosis based on the conventional immunohistoche...
Autores principales: | Baldauf, Michaela C., Orth, Martin F., Dallmayer, Marlene, Marchetto, Aruna, Gerke, Julia S., Rubio, Rebeca Alba, Kiran, Merve M., Musa, Julian, Knott, Maximilian M. L., Ohmura, Shunya, Li, Jing, Akpolat, Nusret, Akatli, Ayse N., Özen, Özlem, Dirksen, Uta, Hartmann, Wolfgang, de Alava, Enrique, Baumhoer, Daniel, Sannino, Giuseppina, Kirchner, Thomas, Grünewald, Thomas G. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788584/ https://www.ncbi.nlm.nih.gov/pubmed/29416716 http://dx.doi.org/10.18632/oncotarget.20098 |
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