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DHSpred: support-vector-machine-based human DNase I hypersensitive sites prediction using the optimal features selected by random forest

DNase I hypersensitive sites (DHSs) are genomic regions that provide important information regarding the presence of transcriptional regulatory elements and the state of chromatin. Therefore, identifying DHSs in uncharacterized DNA sequences is crucial for understanding their biological functions an...

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Detalles Bibliográficos
Autores principales: Manavalan, Balachandran, Shin, Tae Hwan, Lee, Gwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788611/
https://www.ncbi.nlm.nih.gov/pubmed/29416743
http://dx.doi.org/10.18632/oncotarget.23099