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SIRT1 contributes to neuroendocrine differentiation of prostate cancer

The epigenetic factor SIRT1 can promote prostate cancer progression, but it is unclear whether SIRT1 contributes to neuroendocrine differentiation. In this study, we showed that androgen deprivation can induce reactive oxygen species production and that reactive oxygen species, in turn, activate SIR...

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Detalles Bibliográficos
Autores principales: Ruan, Lin, Wang, Lei, Wang, Xiaosong, He, Ming, Yao, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788616/
https://www.ncbi.nlm.nih.gov/pubmed/29416748
http://dx.doi.org/10.18632/oncotarget.23111