Trichostatin A resistance is facilitated by HIF-1α acetylation in HeLa human cervical cancer cells under normoxic conditions

Trichostatin A (TSA) is an anticancer drug that inhibits histone deacetylases (HDACs). Hypoxia-inducible factor 1 (HIF-1) participates in tumor angiogenesis by upregulating target genes, such as vascular endothelial growth factor (VEGF). In the present study, we investigated whether TSA treatment in...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Wook, Yang, Dong Hee, Park, Sojin, Han, Hae-Kyoung, Park, Jong-Wan, Kim, Bo Yeon, Um, Sung Hee, Moon, Eun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788619/
https://www.ncbi.nlm.nih.gov/pubmed/29416751
http://dx.doi.org/10.18632/oncotarget.23327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788619/
https://www.ncbi.nlm.nih.gov/pubmed/29416751
http://dx.doi.org/10.18632/oncotarget.23327

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