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The sphingosine kinase 2 inhibitor ABC294640 inhibits cervical carcinoma cell growth

ABC294640 is a specific sphingosine kinase 2 (SphK2) inhibitor. The anti-cervical carcinoma activity by ABC294640 was tested in this study. ABC294640 inhibited in vitro growth of the established (C33A and HeLa lines) and primary human cervical carcinoma cells. The SphK2 inhibitor also induced G1-S a...

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Detalles Bibliográficos
Autores principales: Xu, Ling, Jin, Longmei, Yang, Baohua, Wang, Lifeng, Xia, Ziyin, Zhang, Qian, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788647/
https://www.ncbi.nlm.nih.gov/pubmed/29416779
http://dx.doi.org/10.18632/oncotarget.23415