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Dose- and time-dependence of the host-mediated response to paclitaxel therapy: a mathematical modeling approach

It has recently been suggested that pro-tumorigenic host-mediated processes induced in response to chemotherapy counteract the anti-tumor activity of therapy, and thereby decrease net therapeutic outcome. Here we use experimental data to formulate a mathematical model describing the host response to...

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Detalles Bibliográficos
Autores principales: Benguigui, Madeleine, Alishekevitz, Dror, Timaner, Michael, Shechter, Dvir, Raviv, Ziv, Benzekry, Sebastien, Shaked, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788661/
https://www.ncbi.nlm.nih.gov/pubmed/29416793
http://dx.doi.org/10.18632/oncotarget.23514