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Chemotherapy drugs cyclophosphamide, cisplatin and doxorubicin induce germ cell loss in an in vitro model of the prepubertal testis

Long term survival rates for childhood cancers is steadily increasing, however cancer survivors can experience fertility problems as a consequence of chemotherapy treatment. This is particularly problematic for young boys, for whom no fertility preservation treatment is yet established. Here, we hav...

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Detalles Bibliográficos
Autores principales: Smart, Ellie, Lopes, Federica, Rice, Siobhan, Nagy, Boglarka, Anderson, Richard A., Mitchell, Rod T., Spears, Norah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788858/
https://www.ncbi.nlm.nih.gov/pubmed/29379115
http://dx.doi.org/10.1038/s41598-018-19761-9