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Chemotherapy drugs cyclophosphamide, cisplatin and doxorubicin induce germ cell loss in an in vitro model of the prepubertal testis
Long term survival rates for childhood cancers is steadily increasing, however cancer survivors can experience fertility problems as a consequence of chemotherapy treatment. This is particularly problematic for young boys, for whom no fertility preservation treatment is yet established. Here, we hav...
Autores principales: | Smart, Ellie, Lopes, Federica, Rice, Siobhan, Nagy, Boglarka, Anderson, Richard A., Mitchell, Rod T., Spears, Norah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788858/ https://www.ncbi.nlm.nih.gov/pubmed/29379115 http://dx.doi.org/10.1038/s41598-018-19761-9 |
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