Cyclic AMP Pathway Suppress Autoimmune Neuroinflammation by Inhibiting Functions of Encephalitogenic CD4 T Cells and Enhancing M2 Macrophage Polarization at the Site of Inflammation

Although it has been demonstrated that cAMP pathway affect both adaptive and innate cell functions, the role of this pathway in the regulation of T-cell-mediated central nervous system (CNS) autoimmune inflammation, such as in experimental autoimmune encephalomyelitis (EAE), remains unclear. It is a...

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Detalles Bibliográficos
Autores principales: Veremeyko, Tatyana, Yung, Amanda W. Y., Dukhinova, Marina, Kuznetsova, Inna S., Pomytkin, Igor, Lyundup, Alexey, Strekalova, Tatyana, Barteneva, Natasha S., Ponomarev, Eugene D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788911/
https://www.ncbi.nlm.nih.gov/pubmed/29422898
http://dx.doi.org/10.3389/fimmu.2018.00050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788911/
https://www.ncbi.nlm.nih.gov/pubmed/29422898
http://dx.doi.org/10.3389/fimmu.2018.00050

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