Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses

Recent advances using CRISPR-Cas9 approaches have dramatically enhanced the ease for genetic manipulation in rodents. Notwithstanding, the methods to deliver nucleic acids into pre-implantation embryos have hardly changed since the original description of mouse transgenesis more than 30 years ago. H...

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Detalles Bibliográficos
Autores principales: Yoon, Yeonsoo, Wang, Dan, Tai, Phillip W. L., Riley, Joy, Gao, Guangping, Rivera-Pérez, Jaime A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788975/
https://www.ncbi.nlm.nih.gov/pubmed/29379011
http://dx.doi.org/10.1038/s41467-017-02706-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788975/
https://www.ncbi.nlm.nih.gov/pubmed/29379011
http://dx.doi.org/10.1038/s41467-017-02706-7

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