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Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses

Recent advances using CRISPR-Cas9 approaches have dramatically enhanced the ease for genetic manipulation in rodents. Notwithstanding, the methods to deliver nucleic acids into pre-implantation embryos have hardly changed since the original description of mouse transgenesis more than 30 years ago. H...

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Detalles Bibliográficos
Autores principales:	Yoon, Yeonsoo, Wang, Dan, Tai, Phillip W. L., Riley, Joy, Gao, Guangping, Rivera-Pérez, Jaime A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788975/ https://www.ncbi.nlm.nih.gov/pubmed/29379011 http://dx.doi.org/10.1038/s41467-017-02706-7

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