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Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer

Phosphatidylserine (PS) is a negatively charged phospholipid in all eukaryotic cells that is actively sequestered to the inner leaflet of the cell membrane. Exposure of PS on apoptotic cells is a normal physiological process that triggers their rapid removal by phagocytic engulfment under noninflamm...

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Detalles Bibliográficos
Autores principales: Belzile, Olivier, Huang, Xianming, Gong, Jian, Carlson, Jay, Schroit, Alan J, Brekken, Rolf A, Freimark, Bruce D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788995/
https://www.ncbi.nlm.nih.gov/pubmed/29417044
http://dx.doi.org/10.2147/ITT.S134834