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mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response

The cellular response to DNA damage is an intricate mechanism that involves the interplay among several pathways. In this study, we provide evidence of the roles of the polyadenylation factor cleavage stimulation factor 50 (CstF-50) and the ubiquitin (Ub) escort factor p97 as cofactors of BRCA1/BARD...

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Detalles Bibliográficos
Autores principales: Fonseca, Danae, Baquero, Jorge, Murphy, Michael R., Aruggoda, Gamage, Varriano, Sophia, Sapienza, Carmen, Mashadova, Oksana, Rahman, Shadaqur, Kleiman, Frida E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789026/
https://www.ncbi.nlm.nih.gov/pubmed/29180510
http://dx.doi.org/10.1128/MCB.00364-17