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Pharmacokinetics and in vitro/in vivo antitumor efficacy of aptamer-targeted Ecoflex(®) nanoparticles for docetaxel delivery in ovarian cancer

PURPOSE: Epithelixal ovarian cancer is the fourth cause of cancer death in developed countries with 77% of ovarian cancer cases diagnosed with regional or distant metastasis, with poor survival rates. Docetaxel (DTX) is a well-known anticancer agent, with clinically proven efficacy in several malign...

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Detalles Bibliográficos
Autores principales: Ghassami, Erfaneh, Varshosaz, Jaleh, Jahanian-Najafabadi, Ali, Minaiyan, Mohsen, Rajabi, Parvin, Hayati, Effat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789074/
https://www.ncbi.nlm.nih.gov/pubmed/29416331
http://dx.doi.org/10.2147/IJN.S152474