Deletion of MCP-1 Impedes Pathogenesis of Acid Ceramidase Deficiency

Farber Disease (FD) is an ultra-rare Lysosomal Storage Disorder caused by deficient acid ceramidase (ACDase) activity. Patients with ACDase deficiency manifest a spectrum of symptoms including formation of nodules, painful joints, and a hoarse voice. Classic FD patients will develop histiocytes in o...

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Detalles Bibliográficos
Autores principales: Yu, Fabian P. S., Dworski, Shaalee, Medin, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789088/
https://www.ncbi.nlm.nih.gov/pubmed/29379059
http://dx.doi.org/10.1038/s41598-018-20052-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789088/
https://www.ncbi.nlm.nih.gov/pubmed/29379059
http://dx.doi.org/10.1038/s41598-018-20052-6

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