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Embelin Restores Carbapenem Efficacy against NDM-1-Positive Pathogens

The emergence and spread of carbapenemase in Gram-negative pathogens poses an enormous threat to global public health. New Delhi metallo-β-lactamase-1 (NDM-1) inactivates nearly every class of β-lactam antibiotics, including carbapenem; however, there is no clinically useful NDM-1 inhibitor. Embelin...

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Detalles Bibliográficos
Autores principales: Ning, Nian-Zhi, Liu, Xiong, Chen, Fanghong, Zhou, Peng, Hu, Lihong, Huang, Jian, Li, Zhan, Huang, Jie, Li, Tao, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789148/
https://www.ncbi.nlm.nih.gov/pubmed/29422890
http://dx.doi.org/10.3389/fmicb.2018.00071