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Evaluation of METase-pemetrexed-loaded PEG–PLGA nanoparticles modified with anti-CD133–scFV for treatment of gastric carcinoma

PEG–PLGA nanoparticles (NPs) modified with anti-CD133 and tumor-targeting single-chain antibody fragment (scFV–NPs) for systemic delivery of methioninase (METase) and pemetrexed for gastric carcinoma were successfully formulated. The structure characterization and biological functions of METase-peme...

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Detalles Bibliográficos
Autores principales: Xin, Lin, Zhang, Hou-Ting, Yang, Wei-Feng, Li, Yi-Fan, Liu, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789153/
https://www.ncbi.nlm.nih.gov/pubmed/29229675
http://dx.doi.org/10.1042/BSR20171001