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Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate

Sodium 4-phenylbutyrate (PB) is an orphan drug for the treatment of urea cycle disorders. It also inhibits the development of endoplasmic reticulum stress, the action of histone deacetylases and as a regulator of the hepatocanalicular transporter. PB is generally considered to have the potential for...

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Detalles Bibliográficos
Autores principales: Kawai, Akito, Yamasaki, Keishi, Enokida, Taisuke, Miyamoto, Shuichi, Otagiri, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789167/
https://www.ncbi.nlm.nih.gov/pubmed/29387812
http://dx.doi.org/10.1016/j.bbrep.2018.01.006