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mTOR Pathways in Cancer and Autophagy

TOR (target of rapamycin), an evolutionarily-conserved serine/threonine kinase, acts as a central regulator of cell growth, proliferation and survival in response to nutritional status, growth factor, and stress signals. It plays a crucial role in coordinating the balance between cell growth and cel...

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Detalles Bibliográficos
Autores principales: Paquette, Mathieu, El-Houjeiri, Leeanna, Pause, Arnim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789368/
https://www.ncbi.nlm.nih.gov/pubmed/29329237
http://dx.doi.org/10.3390/cancers10010018