Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8(+) T cells

Upon infection with an intracellular pathogen, cytotoxic CD8(+) T cells develop diverse differentiation states characterized by function, localization, longevity, and the capacity for self-renewal. The program of differentiation is determined, in part, by FOXO1, a transcription factor known to integ...

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Detalles Bibliográficos
Autores principales: Delpoux, Arnaud, Michelini, Rodrigo Hess, Verma, Shilpi, Lai, Chen-Yen, Omilusik, Kyla D., Utzschneider, Daniel T., Redwood, Alec J., Goldrath, Ananda W., Benedict, Chris A., Hedrick, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789410/
https://www.ncbi.nlm.nih.gov/pubmed/29282254
http://dx.doi.org/10.1084/jem.20170697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789410/
https://www.ncbi.nlm.nih.gov/pubmed/29282254
http://dx.doi.org/10.1084/jem.20170697

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