Targeting IRF3 as a YAP agonist therapy against gastric cancer

The Hippo pathway plays a vital role in tissue homeostasis and tumorigenesis. The transcription factor IRF3 is essential for innate antiviral immunity. In this study, we discovered IRF3 as an agonist of Yes-associated protein (YAP). The expression of IRF3 is positively correlated with that of YAP an...

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Detalles Bibliográficos
Autores principales: Jiao, Shi, Guan, Jingmin, Chen, Min, Wang, Wenjia, Li, Chuanchuan, Wang, Yugong, Cheng, Yunfeng, Zhou, Zhaocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789414/
https://www.ncbi.nlm.nih.gov/pubmed/29339449
http://dx.doi.org/10.1084/jem.20171116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789414/
https://www.ncbi.nlm.nih.gov/pubmed/29339449
http://dx.doi.org/10.1084/jem.20171116

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