Evaluating antibody functional activity and strain-specificity of vaccine candidates for malaria in pregnancy using in vitro phagocytosis assays

BACKGROUND: Malaria in pregnancy is a major cause of poor maternal and infant health, and is associated with the sequestration of P. falciparum-infected erythrocytes (IE) in the placenta. The leading vaccine candidate for pregnancy malaria, VAR2CSA, has been shown to induce antibodies that inhibit I...

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Detalles Bibliográficos
Autores principales: Hommel, Mirja, Chan, Jo-Anne, Umbers, Alexandra J., Langer, Christine, Rogerson, Stephen J., Smith, Joseph D., Beeson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789608/
https://www.ncbi.nlm.nih.gov/pubmed/29378634
http://dx.doi.org/10.1186/s13071-018-2653-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789608/
https://www.ncbi.nlm.nih.gov/pubmed/29378634
http://dx.doi.org/10.1186/s13071-018-2653-7

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