Nandrolone‐induced nuclear accumulation of MyoD protein is mediated by Numb, a Notch inhibitor, in C2C12 myoblasts

Signaling via the androgen receptor (AR) stimulates myogenic progenitor differentiation. In addition, myogenic differentiation factor D (MyoD) and Numb, a Notch inhibitor, play key roles in regulating myogenic differentiation. Nandrolone, an anabolic steroid, upregulates both MyoD and Numb expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xin‐Hua, De Gasperi, Rita, Bauman, William A., Cardozo, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789652/
https://www.ncbi.nlm.nih.gov/pubmed/29333723
http://dx.doi.org/10.14814/phy2.13520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789652/
https://www.ncbi.nlm.nih.gov/pubmed/29333723
http://dx.doi.org/10.14814/phy2.13520

Ejemplares similares