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A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis

We have developed a renewable, scalable and transgene free human blood-brain barrier model, composed of brain endothelial cells (BECs), generated from human amniotic fluid derived induced pluripotent stem cells (AF-iPSC), which can also give rise to syngeneic neural cells of the neurovascular unit....

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Detalles Bibliográficos
Autores principales: Ribecco-Lutkiewicz, Maria, Sodja, Caroline, Haukenfrers, Julie, Haqqani, Arsalan S., Ly, Dao, Zachar, Peter, Baumann, Ewa, Ball, Marguerite, Huang, Jez, Rukhlova, Marina, Martina, Marzia, Liu, Qing, Stanimirovic, Danica, Jezierski, Anna, Bani-Yaghoub, Mahmud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789839/
https://www.ncbi.nlm.nih.gov/pubmed/29382846
http://dx.doi.org/10.1038/s41598-018-19522-8