Cargando…

A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis

We have developed a renewable, scalable and transgene free human blood-brain barrier model, composed of brain endothelial cells (BECs), generated from human amniotic fluid derived induced pluripotent stem cells (AF-iPSC), which can also give rise to syngeneic neural cells of the neurovascular unit....

Descripción completa

Detalles Bibliográficos
Autores principales:	Ribecco-Lutkiewicz, Maria, Sodja, Caroline, Haukenfrers, Julie, Haqqani, Arsalan S., Ly, Dao, Zachar, Peter, Baumann, Ewa, Ball, Marguerite, Huang, Jez, Rukhlova, Marina, Martina, Marzia, Liu, Qing, Stanimirovic, Danica, Jezierski, Anna, Bani-Yaghoub, Mahmud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789839/ https://www.ncbi.nlm.nih.gov/pubmed/29382846 http://dx.doi.org/10.1038/s41598-018-19522-8

Ejemplares similares

Zika virus crosses an in vitro human blood brain barrier model
por: Alimonti, Judie B., et al.
Publicado: (2018)

Mouse embryonic stem cell-derived blood–brain barrier model: applicability to studying antibody triggered receptor mediated transcytosis
por: Jezierski, Anna, et al.
Publicado: (2023)

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood–brain barrier in vitro is dependent on its binding affinity
por: Haqqani, Arsalan S., et al.
Publicado: (2018)

Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human
por: Zhang, Wandong, et al.
Publicado: (2020)

Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells
por: Haqqani, Arsalan S, et al.
Publicado: (2013)

Intercellular Interactomics of Human Brain Endothelial Cells and Th17 Lymphocytes: A Novel Strategy for Identifying Therapeutic Targets of CNS Inflammation
por: Haqqani, Arsalan S., et al.
Publicado: (2011)

Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat
por: Zhang, Wandong, et al.
Publicado: (2023)

Proteome of the Luminal Surface of the Blood–Brain Barrier
por: Hill, Jennifer J., et al.
Publicado: (2021)

Application of blood brain barrier models in pre-clinical assessment of glioblastoma-targeting CAR-T based immunotherapies
por: Huang, Jez, et al.
Publicado: (2022)

Differentiation of Adipose-Derived Stem Cells into Vascular Smooth Muscle Cells for Tissue Engineering Applications
por: Yogi, Alvaro, et al.
Publicado: (2021)

Human Amniotic Fluid Cells Form Functional Gap Junctions with Cortical Cells
por: Jezierski, Anna, et al.
Publicado: (2012)

Pharmacokinetics and Pharmacodynamic Effect of a Blood-Brain Barrier-Crossing Fusion Protein Therapeutic for Alzheimer’s Disease in Rat and Dog
por: Lessard, Etienne, et al.
Publicado: (2022)

Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor
por: Yogi, Alvaro, et al.
Publicado: (2022)

Transcytosis in thyroid follicle cells
Publicado: (1983)

Transcytosis of albumin in capillary endothelium
Publicado: (1987)

Transcytosis of Staphylococcal Superantigen Toxins
por: Hamad, Abdel Rahim A., et al.
Publicado: (1997)

Endocytosis and transcytosis of gliadin peptides
por: Barone, M. Vittoria, et al.
Publicado: (2016)

Endothelial Transcytosis of Lipoproteins in Atherosclerosis
por: Zhang, Xinbo, et al.
Publicado: (2018)

Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity
por: Caron, Nicholas S, et al.
Publicado: (2022)

A novel mechanism of HIV transcytosis and infection
por: Gupta, S, et al.
Publicado: (2012)

A Human Blood-Brain Barrier Transcytosis Assay Reveals Antibody Transcytosis Influenced by pH-Dependent Receptor Binding
por: Sade, Hadassah, et al.
Publicado: (2014)

Enhancement of Polymeric Immunoglobulin Receptor Transcytosis by Biparatopic VHH
por: Emmerson, Chris D., et al.
Publicado: (2011)

Glycolipid-dependent and lectin-driven transcytosis in mouse enterocytes
por: Ivashenka, Alena, et al.
Publicado: (2021)

The Role of BAR Proteins and the Glycocalyx in Brain Endothelium Transcytosis
por: Leite, Diana M., et al.
Publicado: (2020)

Unraveling GLUT‐mediated transcytosis pathway of glycosylated nanodisks
por: Wang, Huan, et al.
Publicado: (2021)

Application of In vitro transcytosis models to brain targeted biologics
por: Deng, Kangwen, et al.
Publicado: (2023)

GRP75 as a functional element of cholix transcytosis
por: Liu, Keyi, et al.
Publicado: (2022)

Amniotic Stem Cells: Potential in Regenerative Medicine
por: Bani-Yaghoub, Mahmud, et al.
Publicado: (2012)

Neuralized Promotes Basal to Apical Transcytosis of Delta in Epithelial Cells
por: Benhra, Najate, et al.
Publicado: (2010)

LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers
por: Magalhaes, Ana, et al.
Publicado: (2016)

Transcytosis of TrkA leads to diversification of dendritic signaling endosomes
por: Barford, Kelly, et al.
Publicado: (2018)

Transcytosis to Cross the Blood Brain Barrier, New Advancements and Challenges
por: Pulgar, Victor M.
Publicado: (2019)

Intracellular transport and regulation of transcytosis across the blood–brain barrier
por: Villaseñor, Roberto, et al.
Publicado: (2018)

In vivo clearance of nanoparticles by transcytosis across alveolar epithelial cells
por: Detampel, Pascal, et al.
Publicado: (2019)

Suppression of transcytosis regulates zebrafish blood-brain barrier function
por: O'Brown, Natasha M, et al.
Publicado: (2019)

Chemical biology tools for probing transcytosis at the blood–brain barrier
por: Beard, Rhiannon, et al.
Publicado: (2019)

Atherogenesis, Transcytosis, and the Transmural Cholesterol Flux: A Critical Review
por: Goldberg, Doron, et al.
Publicado: (2022)

Receptor-Mediated Transcytosis of Leptin through Human Intestinal Cells In Vitro
por: Cammisotto, Philippe G., et al.
Publicado: (2010)

Specific IgA Enhances the Transcytosis and Excretion of Hepatitis A Virus
por: Counihan, Natalie A., et al.
Publicado: (2016)

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers
por: Nguyen, Sophie, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0s4sp720st8fgb1virlt920rqe