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Early bone tissue aging in human auditory ossicles is accompanied by excessive hypermineralization, osteocyte death and micropetrosis

Within the mineralized bone, osteocytes form a multifunctional mechanosensitive network orchestrating bone remodelling. A preserved osteocyte population is a crucial determinant of bone quality. In human auditory ossicles, the early decrease in osteocyte numbers but maintained integrity remains an u...

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Detalles Bibliográficos
Autores principales: Rolvien, Tim, Schmidt, Felix N., Milovanovic, Petar, Jähn, Katharina, Riedel, Christoph, Butscheidt, Sebastian, Püschel, Klaus, Jeschke, Anke, Amling, Michael, Busse, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789841/
https://www.ncbi.nlm.nih.gov/pubmed/29382878
http://dx.doi.org/10.1038/s41598-018-19803-2