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Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors

Drug-resistant superbugs pose a huge threat to human health. Infections by Enterobacteriaceae producing metallo-β-lactamases (MBLs), e.g., New Delhi metallo-β-lactamase 1 (NDM-1) are very difficult to treat. Development of effective MBL inhibitors to revive the efficacy of existing antibiotics is hi...

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Detalles Bibliográficos
Autores principales: Wang, Runming, Lai, Tsz-Pui, Gao, Peng, Zhang, Hongmin, Ho, Pak-Leung, Woo, Patrick Chiu-Yat, Ma, Guixing, Kao, Richard Yi-Tsun, Li, Hongyan, Sun, Hongzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789847/
https://www.ncbi.nlm.nih.gov/pubmed/29382822
http://dx.doi.org/10.1038/s41467-018-02828-6