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Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody

Tick-borne encephalitis virus (TBEV) causes 13,000 cases of human meningitis and encephalitis annually. However, the structure of the TBEV virion and its interactions with antibodies are unknown. Here, we present cryo-EM structures of the native TBEV virion and its complex with Fab fragments of neut...

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Detalles Bibliográficos
Autores principales: Füzik, Tibor, Formanová, Petra, Růžek, Daniel, Yoshii, Kentaro, Niedrig, Matthias, Plevka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789857/
https://www.ncbi.nlm.nih.gov/pubmed/29382836
http://dx.doi.org/10.1038/s41467-018-02882-0