Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy

It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 CpGs) and gene expression analysis after muscle hypertrophy (loading), return of muscle mass to baseline (unloading),...

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Detalles Bibliográficos
Autores principales: Seaborne, Robert A., Strauss, Juliette, Cocks, Matthew, Shepherd, Sam, O’Brien, Thomas D., van Someren, Ken A., Bell, Phillip G., Murgatroyd, Christopher, Morton, James P., Stewart, Claire E., Sharples, Adam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789890/
https://www.ncbi.nlm.nih.gov/pubmed/29382913
http://dx.doi.org/10.1038/s41598-018-20287-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789890/
https://www.ncbi.nlm.nih.gov/pubmed/29382913
http://dx.doi.org/10.1038/s41598-018-20287-3

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