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Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy
It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 CpGs) and gene expression analysis after muscle hypertrophy (loading), return of muscle mass to baseline (unloading),...
Autores principales: | Seaborne, Robert A., Strauss, Juliette, Cocks, Matthew, Shepherd, Sam, O’Brien, Thomas D., van Someren, Ken A., Bell, Phillip G., Murgatroyd, Christopher, Morton, James P., Stewart, Claire E., Sharples, Adam P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789890/ https://www.ncbi.nlm.nih.gov/pubmed/29382913 http://dx.doi.org/10.1038/s41598-018-20287-3 |
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