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PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection

Efforts to knock out Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) from asexual erythrocytic stage have not been successful, indicating an indispensable role of the enzyme in asexual growth. We recently reported generation of a transgenic parasite with mutant CDPK1 [Bansal A, et...

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Detalles Bibliográficos
Autores principales: Bansal, Abhisheka, Molina-Cruz, Alvaro, Brzostowski, Joseph, Liu, Poching, Luo, Yan, Gunalan, Karthigayan, Li, Yuesheng, Ribeiro, José M. C., Miller, Louis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789930/
https://www.ncbi.nlm.nih.gov/pubmed/29311293
http://dx.doi.org/10.1073/pnas.1715443115