Structure of the C1r–C1s interaction of the C1 complex of complement activation

The multiprotein complex C1 initiates the classical pathway of complement activation on binding to antibody–antigen complexes, pathogen surfaces, apoptotic cells, and polyanionic structures. It is formed from the recognition subcomponent C1q and a tetramer of proteases C1r(2)C1s(2) as a Ca(2+)-depen...

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Detalles Bibliográficos
Autores principales: Almitairi, Jamal O. M., Venkatraman Girija, Umakhanth, Furze, Christopher M., Simpson-Gray, Xanthe, Badakshi, Farah, Marshall, Jamie E., Schwaeble, Wilhelm J., Mitchell, Daniel A., Moody, Peter C. E., Wallis, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789954/
https://www.ncbi.nlm.nih.gov/pubmed/29311313
http://dx.doi.org/10.1073/pnas.1718709115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789954/
https://www.ncbi.nlm.nih.gov/pubmed/29311313
http://dx.doi.org/10.1073/pnas.1718709115

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