ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells

Mutations in anaplastic lymphoma kinase (ALK) are implicated in somatic and familial neuroblastoma, a pediatric tumor of neural crest-derived tissues. Recently, biochemical analyses have identified secreted small ALKAL proteins (FAM150, AUG) as potential ligands for human ALK and the related leukocy...

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Detalles Bibliográficos
Autores principales: Fadeev, Andrey, Mendoza-Garcia, Patricia, Irion, Uwe, Guan, Jikui, Pfeifer, Kathrin, Wiessner, Stephanie, Serluca, Fabrizio, Singh, Ajeet Pratap, Nüsslein-Volhard, Christiane, Palmer, Ruth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789956/
https://www.ncbi.nlm.nih.gov/pubmed/29317532
http://dx.doi.org/10.1073/pnas.1719137115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789956/
https://www.ncbi.nlm.nih.gov/pubmed/29317532
http://dx.doi.org/10.1073/pnas.1719137115

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