Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms

Biofilms represent a multicellular growth state of bacteria that are intrinsically resistant to conventional antibiotics. It was recently shown that a synthetic immunomodulatory cationic peptide, 1018 (VRLIVAVRIWRR-NH(2)), exhibits broad-spectrum antibiofilm activity but the sequence determinants of...

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Detalles Bibliográficos
Autores principales: Haney, Evan F., Brito-Sánchez, Yoan, Trimble, Michael J., Mansour, Sarah C., Cherkasov, Artem, Hancock, Robert E. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789975/
https://www.ncbi.nlm.nih.gov/pubmed/29382854
http://dx.doi.org/10.1038/s41598-018-19669-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789975/
https://www.ncbi.nlm.nih.gov/pubmed/29382854
http://dx.doi.org/10.1038/s41598-018-19669-4

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