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Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms

Biofilms represent a multicellular growth state of bacteria that are intrinsically resistant to conventional antibiotics. It was recently shown that a synthetic immunomodulatory cationic peptide, 1018 (VRLIVAVRIWRR-NH(2)), exhibits broad-spectrum antibiofilm activity but the sequence determinants of...

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Detalles Bibliográficos
Autores principales:	Haney, Evan F., Brito-Sánchez, Yoan, Trimble, Michael J., Mansour, Sarah C., Cherkasov, Artem, Hancock, Robert E. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789975/ https://www.ncbi.nlm.nih.gov/pubmed/29382854 http://dx.doi.org/10.1038/s41598-018-19669-4

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