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Dynamic cellular phenotyping defines specific mobilization mechanisms of human hematopoietic stem and progenitor cells induced by SDF1α versus synthetic agents

Efficient mobilization of hematopoietic stem and progenitor cells (HSPC) is one of the most crucial issues for harvesting an adequate amount of peripheral HSPC for successful clinical transplantation. Applying well-defined surrogate models for the bone marrow niche, live cell imaging techniques, and...

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Detalles Bibliográficos
Autores principales: Monzel, Cornelia, Becker, Alexandra S., Saffrich, Rainer, Wuchter, Patrick, Eckstein, Volker, Ho, Anthony D., Tanaka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789976/
https://www.ncbi.nlm.nih.gov/pubmed/29382856
http://dx.doi.org/10.1038/s41598-018-19557-x