Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains

Despite more than three decades of multidrug therapy (MDT), leprosy remains a major public health issue in several endemic countries, including India. The emergence of drug resistance in Mycobacterium leprae (M. leprae) is a cause of concern and poses a threat to the leprosy-control program, which m...

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Detalles Bibliográficos
Autores principales: Lavania, Mallika, Singh, Itu, Turankar, Ravindra P, Gupta, Anuj Kumar, Ahuja, Madhvi, Pathak, Vinay, Sengupta, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790067/
https://www.ncbi.nlm.nih.gov/pubmed/29416362
http://dx.doi.org/10.2147/IDR.S152082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790067/
https://www.ncbi.nlm.nih.gov/pubmed/29416362
http://dx.doi.org/10.2147/IDR.S152082

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