A non-synonymous polymorphism in NBS1 is associated with progression from chronic hepatitis B virus infection to hepatocellular carcinoma in a Chinese population

PURPOSE: Nijmegen breakage syndrome 1 (NBS1) has a vital role in DNA double-strand break (DSB) repair, functioning as a sensor to identify and repair DNA damage and maintaining genomic stability by participating in the intra-S-phase checkpoint. Polymorphisms of NBS1 have been investigated in multipl...

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Detalles Bibliográficos
Autores principales: Zhen, Ya’nan, Xiao, Ruixue, Chen, Xing, Yuan, Changjin, Sun, Yanlai, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790086/
https://www.ncbi.nlm.nih.gov/pubmed/29416357
http://dx.doi.org/10.2147/OTT.S153538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790086/
https://www.ncbi.nlm.nih.gov/pubmed/29416357
http://dx.doi.org/10.2147/OTT.S153538

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