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Quantitative MRI in early intervertebral disc degeneration: T1rho correlates better than T2 and ADC with biomechanics, histology and matrix content

INTRODUCTION: Low-back pain (LBP) has been correlated to the presence of intervertebral disc (IVD) degeneration on T2-weighted (T2w) MRI. It remains challenging, however, to accurately stage degenerative disc disease (DDD) based on T2w MRI and measurements of IVD height, particularly for early DDD....

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Detalles Bibliográficos
Autores principales: Paul, Cornelis P. L., Smit, Theodoor H., de Graaf, Magda, Holewijn, Roderick M., Bisschop, Arno, van de Ven, Peter M., Mullender, Margriet G., Helder, Marco N., Strijkers, Gustav J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790235/
https://www.ncbi.nlm.nih.gov/pubmed/29381716
http://dx.doi.org/10.1371/journal.pone.0191442