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The conserved basic residues and the charged amino acid residues at the α-helix of the zinc finger motif regulate the nuclear transport activity of triple C(2)H(2) zinc finger proteins

Zinc finger (ZF) motifs on proteins are frequently recognized as a structure for DNA binding. Accumulated reports indicate that ZF motifs contain nuclear localization signal (NLS) to facilitate the transport of ZF proteins into nucleus. We investigated the critical factors that facilitate the nuclea...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Ying, Lin, Lih-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790263/
https://www.ncbi.nlm.nih.gov/pubmed/29381770
http://dx.doi.org/10.1371/journal.pone.0191971