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Brief report: Circulating markers of fibrosis are associated with immune reconstitution status in HIV-infected men

INTRODUCTION: Lymphoid tissue fibrosis may contribute to incomplete immune reconstitution on antiretroviral therapy (ART) via local CD4(+) T lymphocyte (CD4) depletion. Hyaluronic acid (HA) increases with fibrotic burden. CXCL4 concentrations increase in response to pro-fibrotic stimuli, but lower C...

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Detalles Bibliográficos
Autores principales: Tobolowsky, F. A., Wada, N., Martinez-Maza, O., Magpantay, L., Koletar, S. L., Palella, F. J., Brown, T. T., Lake, J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790272/
https://www.ncbi.nlm.nih.gov/pubmed/29381717
http://dx.doi.org/10.1371/journal.pone.0191606