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Lack of MHC class II molecules favors CD8(+) T-cell infiltration into tumors associated with an increased control of tumor growth

Regulatory T-cells (Tregs) are crucial for the maintenance of immune tolerance and homeostasis as well as for preventing autoimmune diseases, but their impact on the survival of cancer patients remains controversial. In the TC-1 mouse model of human papillomavirus (HPV)-related carcinoma, we have pr...

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Detalles Bibliográficos
Autores principales: Chaoul, Nada, Tang, Alexandre, Desrues, Belinda, Oberkampf, Marine, Fayolle, Catherine, Ladant, Daniel, Sainz-Perez, Alexander, Leclerc, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790350/
https://www.ncbi.nlm.nih.gov/pubmed/29399403
http://dx.doi.org/10.1080/2162402X.2017.1404213