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Association of p53 and mitochondrial gene with chemosensitization by metformin in ovarian cancer
OBJECTIVE: This study aims to investigate the association of p53 and D-loop gene with drug resistance and sensitization induced by metformin in ovarian cancer. RESULTS: Metformin suppresses cells in a time-dependent manner, but the inhibition does not change with the dose of metformin. This suggests...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790438/ https://www.ncbi.nlm.nih.gov/pubmed/29423021 http://dx.doi.org/10.18632/oncotarget.22863 |