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Association of p53 and mitochondrial gene with chemosensitization by metformin in ovarian cancer

OBJECTIVE: This study aims to investigate the association of p53 and D-loop gene with drug resistance and sensitization induced by metformin in ovarian cancer. RESULTS: Metformin suppresses cells in a time-dependent manner, but the inhibition does not change with the dose of metformin. This suggests...

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Detalles Bibliográficos
Autores principales: Wei, De-Hua, Wang, Yan, Shi, Hui-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790438/
https://www.ncbi.nlm.nih.gov/pubmed/29423021
http://dx.doi.org/10.18632/oncotarget.22863